Anti-AMIGO2 antibody (C-Term) (STJA0005769)

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STJA0005769-100
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Short Description :Rabbit polyclonal anti-Alivin1 (C-Term) for use in WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Purification:Antigen Affinity Purified
Dilution Range:WB 1:500-1:1000
Formulation:PBS + 0.02% NaN3
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:AMIGO2
Gene ID:347902
Uniprot ID:AMGO2_HUMAN
Immunogen:Synthetic peptide corresponding to amino acids from the C-terminal region of mouse Alivin1
Immunogen Region:C-Term
Specificity:Reacts with the C-terminal region of mouse and rat Alivin1
Function Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Protein Name Amphoterin-Induced Protein 2
Amigo-2
Alivin-1
Differentially Expressed In Gastric Adenocarcinomas
Dega
Database Links Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Nucleus
Associated With Nucleus As Well As Plasma Membrane
Restricted To Somata Of Cerebellar As Well As Hippocampal Neurons
Alternative Antibody Names Anti-Amphoterin-Induced Protein 2 antibody
Anti-Amigo-2 antibody
Anti-Alivin-1 antibody
Anti-Differentially Expressed In Gastric Adenocarcinomas antibody
Anti-Dega antibody
Anti-AMIGO2 antibody
Anti-ALI1 antibody

Information sourced from Uniprot.org

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