• Human prostate carcinoma stained anti-AMACR, anti-p63 and anti-HMW CK 34βE12 antibodies using peroxidase-conjugate and DAB chromogens. Note cytoplasmic and luminal circumferential staining of carcinoma glands with AMACR and basal cell staining with p63 and HMW CK 34βE12.

Anti-AMACR+P63+HMW CK antibody [13H4+4A4+34 Beta E12] (STJ180008)

SKU:
STJ180008

£248.50 - £1,249.50
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Host: Rabbit, Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit, Mouse monoclonal antibody anti-AMACR+P63+HMW CK is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 13H4+4A4+34 Beta E12
Conjugation: Unconjugated
Isotype: IgG, IgG1a/k + IgG2a
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:50
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: AMACR
Gene ID: 23600
Uniprot ID: AMACR_HUMAN
Specificity: Positive control: Prostate intraepithelial neoplasia (PIN)
Immunogen: Human AMACR (P504S) , p63, and CKHMW (34 Beta E12) polypeptides
Function Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs.
Protein Name Alpha-Methylacyl-Coa Racemase
2-Methylacyl-Coa Racemase
Database Links Reactome: R-HSA-193368
Reactome: R-HSA-193775
Reactome: R-HSA-389887
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Mitochondrion
Alternative Antibody Names Anti-Alpha-Methylacyl-Coa Racemase antibody
Anti-2-Methylacyl-Coa Racemase antibody
Anti-AMACR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance