Anti-AMACR+p63 antibody [13H4+4A4] (STJ180007)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit, Mouse
ConjugationUnconjugated
IsotypeIgG/IgG1ak
ImmunogenHuman AMACR (P504S) and p63 polypeptides
General Information
| Short Description | Rabbit, Mouse monoclonal AMACR+p63 antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit, Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 13H4+4A4 |
| Isotype | IgG/IgG1ak |
| Conjugation | Unconjugated |
| Purification | Affinity purified |
| Dilution Range | 1:50 |
| Formulation | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction | Store at 2β8Β°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate labβstandardized diluent. Stability after dilution: 7 days at 24Β°C, 3 months at 2β8Β°C, 6months at β20Β°C. |
Target Information
| Gene Symbol | AMACR |
| Gene ID | 23600 |
| Uniprot ID | AMACR_HUMAN |
| Immunogen | Human AMACR (P504S) and p63 polypeptides |
| Specificity | Positive control: Prostate carcinoma |
Additional Info
| Function | Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. |
| Protein Name | Alpha-Methylacyl-Coa Racemase2-Methylacyl-Coa Racemase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeMitochondrion |
| Alternative Antibody Names | Anti-Alpha-Methylacyl-Coa Racemase antibodyAnti-2-Methylacyl-Coa Racemase antibodyAnti-AMACR antibody |
Information sourced from Uniprot.org