| Host: | Rabbit |
| Applications: | CM/DB/ELISA/ICC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-AMACR (260-310) is suitable for use in Confocal Microscopy, Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.6 µg/µl |
| Dilution Range: | WB: 1:500DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:200CFM: 1:100 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | AMACR |
| Gene ID: | 23600 |
| Uniprot ID: | AMACR_HUMAN |
| Immunogen Region: | 260-310 |
| Immunogen: | Synthetic peptide taken within amino acid region 260-310 on human alpha-methylacyl-CoA racemase protein. |
| Function | Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. |
| Protein Name | Alpha-Methylacyl-Coa Racemase2-Methylacyl-Coa Racemase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeMitochondrion |
| Alternative Antibody Names | Anti-Alpha-Methylacyl-Coa Racemase antibodyAnti-2-Methylacyl-Coa Racemase antibodyAnti-AMACR antibody |
Information sourced from Uniprot.org
