| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-ALX homeobox protein 1 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALX1 |
| Gene ID: | 8092 |
| Uniprot ID: | ALX1_HUMAN |
| Specificity: | This antibody detects endogenous levels of ALX1 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human ALX1 |
| Post Translational Modifications | Acetylated at Lys-131 by EP300.increases interaction with EP300 and stimulates ALX1 transcriptional activity. |
| Function | Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1. |
| Protein Name | Alx Homeobox Protein 1Cartilage Homeoprotein 1Cart-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Alx Homeobox Protein 1 antibodyAnti-Cartilage Homeoprotein 1 antibodyAnti-Cart-1 antibodyAnti-ALX1 antibodyAnti-CART1 antibody |
Information sourced from Uniprot.org