| Host: | Goat |
| Applications: | Pep-ELISA/FC/IF |
| Reactivity: | Human/Mouse/Rat/Pig/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ALS2CR3/GRIF1 (C-Term) is suitable for use in ELISA, Flow Cytometry and Immunofluorescence research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.IF: Strong expression of the protein seen in U2OS cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | TRAK2 |
| Gene ID: | 66008 |
| Uniprot ID: | TRAK2_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_055864.2 |
| Immunogen Sequence: | CTSSPKMGVLKED |
| Post Translational Modifications | O-glycosylated. |
| Function | May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR. |
| Protein Name | Trafficking Kinesin-Binding Protein 2Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 3 Protein |
| Database Links | Reactome: R-HSA-9013419Reactome: R-HSA-9013425 |
| Cellular Localisation | CytoplasmEarly EndosomeMitochondrionColocalizes With Mgarp At The MitochondriaTranslocates From The Cytoplasm To The Mitochondria In A Mgarp-Dependent Manner |
| Alternative Antibody Names | Anti-Trafficking Kinesin-Binding Protein 2 antibodyAnti-Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 3 Protein antibodyAnti-TRAK2 antibodyAnti-ALS2CR3 antibodyAnti-KIAA0549 antibody |
Information sourced from Uniprot.org