| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC/IF/FC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-Alpha2-antiplasmin (Internal) is suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 70kDa band observed in lysates of cell line HepG2 (calculated MW of 54.6kDa according to NP_000925.2). The observed molecular weight is observed by other sources. Recommended co |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SERPINF2 |
| Gene ID: | 5345 |
| Uniprot ID: | A2AP_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000925.2; NP_001159393.1 |
| Specificity: | This antibody is expected to recognise both reported isoforms (NP_000925.2; NP_001159393.1). Reported variants represent identical protein (NP_000925.2; NP_001159392.1). |
| Immunogen Sequence: | KDFLQSLKGFPRGDK |
| Post Translational Modifications | Proteolytically cleaved at Pro-39 by both the prolyl endopeptidase FAP form and antiplasmin-cleaving enzyme FAP soluble form to generate mature alpha-2-antiplasmin. |
| Function | Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. |
| Protein Name | Alpha-2-AntiplasminAlpha-2-ApAlpha-2-Plasmin InhibitorAlpha-2-PiSerpin F2 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-75205 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Antiplasmin antibodyAnti-Alpha-2-Ap antibodyAnti-Alpha-2-Plasmin Inhibitor antibodyAnti-Alpha-2-Pi antibodyAnti-Serpin F2 antibodyAnti-SERPINF2 antibodyAnti-AAP antibodyAnti-PLI antibody |
Information sourced from Uniprot.org