Anti-Alpha-Actinin antibody [SRM13488] (STJ11108218)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
STJ11108218
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General Information

Short DescriptionRabbit monoclonal Alpha-Actinin-1 antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSRM13488
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB, 1:2000-1:4000
IHC-P, 1:200-1:2000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS containing 50% Glycerol and 0.05% BSA, preserved with proclin300 or Sodium Azide (as specified on the Certificate of Analysis) , pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolACTN1
Gene ID87
Uniprot IDACTN1_HUMAN
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
Immunogen SequenceHuman

Additional Info

Protein Name Alpha-Actinin-1
Alpha-Actinin Cytoskeletal Isoform
F-Actin Cross-Linking Protein
Non-Muscle Alpha-Actinin-1
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-3000170
Reactome: R-HSA-373753
Reactome: R-HSA-446388
Reactome: R-HSA-9013405
Reactome: R-HSA-9013418
Reactome: R-HSA-9035034
Cellular Localisation Cytoplasm
Cytoskeleton
Myofibril
Sarcomere
Z Line
Cell Membrane
Cell Junction
Cell Projection
Ruffle
Colocalizes With Myoz2 And Ppp3ca At The Z-Line Of Heart And Skeletal Muscle
Colocalizes With Psd In Membrane Ruffles And Central Reticular Structures
Alternative Antibody Names Anti-Alpha-Actinin-1 antibody
Anti-Alpha-Actinin Cytoskeletal Isoform antibody
Anti-F-Actin Cross-Linking Protein antibody
Anti-Non-Muscle Alpha-Actinin-1 antibody
Anti-ACTN1 antibody

Information sourced from Uniprot.org

Citations

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