Host: |
Goat |
Applications: |
Pep-ELISA/IF |
Reactivity: |
Human/Mouse/Rat/Dog/Cow |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Goat polyclonal antibody anti-ALMS1 (C-Term) is suitable for use in ELISA and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: |
0.5 mg/mL |
Dilution Range: |
IF-Strong expression of the protein seen in the cytoplasm of HepG2 and HeLa cells. 10µg/mlELISA-antibody detection limit dilution 1:4000. |
Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: |
ALMS1 |
Gene ID: |
7840 |
Uniprot ID: |
ALMS1_HUMAN |
Immunogen Region: |
C-Term |
Accession Number: |
NP_055935.4 |
Specificity: |
The C terminus of ALMS1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react wi |
Immunogen Sequence: |
RVTNQLLGRKVPWD |
Function | Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells. |
Protein Name | Centrosome-Associated Protein Alms1Alstrom Syndrome Protein 1 |
Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodySpindle PoleAssociated With Centrosomes And Basal Bodies At The Base Of Primary CiliaSpecifically Locates To The Proximal Ends Of Centrioles And Basal BodiesColocalizes Partially With Ncapd2 At These SitesDuring Mitosis Localizes To Both Spindle Poles |
Alternative Antibody Names | Anti-Centrosome-Associated Protein Alms1 antibodyAnti-Alstrom Syndrome Protein 1 antibodyAnti-ALMS1 antibodyAnti-KIAA0328 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance