Anti-ALKAL2 antibody (64-114 aa) (STJ195351)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human F150B at the amino acid range 64-114
General Information
| Short Description | Rabbit polyclonal anti-ALK and LTK ligand 2 (64-114 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALKAL2 |
| Gene ID | 285016 |
| Uniprot ID | ALKL2_HUMAN |
| Immunogen | Synthesized peptide derived from the human F150B at the amino acid range 64-114 |
| Immunogen Region | 64-114 aa |
| Specificity | This antibody detects endogenous levels of F150B at Human/Mouse/Rat |
Additional Info
| Function | Cytokine that acts as a physiological ligand for receptor tyrosine kinases LTK and ALK, leading to their activation. Cytokine-binding is sufficient to activate LTK. In contrast, ALKAL2-driven activation of ALK is coupled with heparin-binding to ALK. Stimulation of ALK signaling is involved in neural development and regulation of energy expenditure. |
| Protein Name | Alk And Ltk Ligand 2Augmentor AlphaAug-Alpha |
| Database Links | Reactome: R-HSA-201556Reactome: R-HSA-9842663 |
| Cellular Localisation | SecretedCell MembraneFollowing Interaction With Receptor Tyrosine Kinase AlkAssociates With The Cell MembraneMembrane-Binding Is Required To Activate Alk |
| Alternative Antibody Names | Anti-Alk And Ltk Ligand 2 antibodyAnti-Augmentor Alpha antibodyAnti-Aug-Alpha antibodyAnti-ALKAL2 antibodyAnti-FAM150B antibodyAnti-UNQ542 antibodyAnti-PRO1097 antibody |
Information sourced from Uniprot.org