Tissue Specificity | Detected in brain (at protein level). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole. |
Function | Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines. |
Protein Name | 4-Trimethylaminobutyraldehyde DehydrogenaseTmaba-DhTmabaldhAldehyde Dehydrogenase E3 IsozymeAldehyde Dehydrogenase Family 9 Member A1Formaldehyde DehydrogenaseGamma-Aminobutyraldehyde DehydrogenaseR-Aminobutyraldehyde Dehydrogenase Cleaved Into - 4-Trimethylaminobutyraldehyde Dehydrogenase - N-Terminally Processed |
Database Links | Reactome: R-HSA-71262 |
Cellular Localisation | CytoplasmCytosol |
Alternative Antibody Names | Anti-4-Trimethylaminobutyraldehyde Dehydrogenase antibodyAnti-Tmaba-Dh antibodyAnti-Tmabaldh antibodyAnti-Aldehyde Dehydrogenase E3 Isozyme antibodyAnti-Aldehyde Dehydrogenase Family 9 Member A1 antibodyAnti-Formaldehyde Dehydrogenase antibodyAnti-Gamma-Aminobutyraldehyde Dehydrogenase antibodyAnti-R-Aminobutyraldehyde Dehydrogenase Cleaved Into - 4-Trimethylaminobutyraldehyde Dehydrogenase - N-Terminally Processed antibodyAnti-ALDH9A1 antibodyAnti-ALDH4 antibodyAnti-ALDH7 antibodyAnti-ALDH9 antibody |
Information sourced from Uniprot.org