| Host: | Goat |
| Applications: | Pep-ELISA/WB/IHC |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ALDH3A1 (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 55kDa band observed in Mouse Eye lysates (calculated MW of 50.5kDa according to Mouse NP_031462.2). Recommended concentration: 0.01-0.03µg/ml.IHC: In paraffin embedded Huma |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ALDH3A1 |
| Gene ID: | 218 |
| Uniprot ID: | AL3A1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_000682.3 |
| Specificity: | Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1 |
| Immunogen Sequence: | RYPPSPAKMTQH |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light. |
| Protein Name | Aldehyde Dehydrogenase - Dimeric Nadp-PreferringAldhiiiAldehyde Dehydrogenase 3Aldehyde Dehydrogenase Family 3 Member A1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase - Dimeric Nadp-Preferring antibodyAnti-Aldhiii antibodyAnti-Aldehyde Dehydrogenase 3 antibodyAnti-Aldehyde Dehydrogenase Family 3 Member A1 antibodyAnti-ALDH3A1 antibodyAnti-ALDH3 antibody |
Information sourced from Uniprot.org