| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Cow/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-ALDH2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 50kDa band observed in Human, Mouse and Rat Liver lysates (calculated MW of 56.4kDa according to Human NP_000681.2 amd 56.5kDa according to Mouse NP_033786.1). Recommended concen |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | ALDH2 |
| Gene ID: | 217 |
| Uniprot ID: | ALDH2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_000681.2; NP_001191818.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_000681.2; NP_001191818.1). |
| Immunogen Sequence: | DETQFKKILGYIN |
| Function | Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage. |
| Protein Name | Aldehyde Dehydrogenase - MitochondrialAldh Class 2Aldh-E2Aldhi |
| Database Links | Reactome: R-HSA-380612Reactome: R-HSA-445355Reactome: R-HSA-71384Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase - Mitochondrial antibodyAnti-Aldh Class 2 antibodyAnti-Aldh-E2 antibodyAnti-Aldhi antibodyAnti-ALDH2 antibodyAnti-ALDM antibody |
Information sourced from Uniprot.org
