• Western blot analysis of extracts of various cell lines, using ALDH2 antibody (STJ115424) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-ALDH2 antibody (1-380) (STJ115424)

SKU:
STJ115424

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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ALDH2 (1-380) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ALDH2
Gene ID: 217
Uniprot ID: ALDH2_HUMAN
Immunogen Region: 1-380
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human ALDH2 (NP_000681.2).
Immunogen Sequence: MLRAAARFGPRLGRRLLSAA ATQAVPAPNQQPEVFCNQIF INNEWHDAVSRKTFPTVNPS TGEVICQVAEGDKEDVDKAV KAARAAFQLGSPWRRMDASH RGRLLNRLADLIERDRTYLA ALETLDNGKPYVISYLVDLD MVLKCLRYYAGWADKYHGKT IPIDGDFFSYTRHEPVGVCG QIIPWNFPLLMQAWKLGPAL ATGNVVVMKVAEQTPLTALY VANLIKEAGFPPGVVNIVP
Function Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage.
Protein Name Aldehyde Dehydrogenase - Mitochondrial
Aldh Class 2
Aldh-E2
Aldhi
Database Links Reactome: R-HSA-380612
Reactome: R-HSA-445355
Reactome: R-HSA-71384
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Aldehyde Dehydrogenase - Mitochondrial antibody
Anti-Aldh Class 2 antibody
Anti-Aldh-E2 antibody
Anti-Aldhi antibody
Anti-ALDH2 antibody
Anti-ALDM antibody

Information sourced from Uniprot.org

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