| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDH1L2 |
| Gene ID: | 160428 |
| Uniprot ID: | AL1L2_HUMAN |
| Immunogen Region: | 280-480 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2). |
| Immunogen Sequence: | EPLEIKGAKKPGLVTKNGLV LFGNDGKALTVRNLQFEDGK MIPASQYFSTGETSVVELTA EEVKVAETIKVIWAGILSNV PIIEDSTDFFKSGASSMDVA RLVEEIRQKCGGLQLQNEDV YMATKFEGFIQKVVRKLRGE DQEVELVVDYISKEVNEIMV KMPYQCFINGQFTDADDGKT YDTINPTDGSTICKVSYASL A |
| Tissue Specificity | Highly expressed in pancreas, heart, brain and skeletal muscle. |
| Post Translational Modifications | Phosphopantetheinylation at Ser-375 by AASDHPPT is required for the formyltetrahydrofolate dehydrogenase activity. |
| Function | Mitochondrial 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide. |
| Protein Name | Mitochondrial 10-Formyltetrahydrofolate DehydrogenaseMitochondrial 10-FthfdhMtfdhAldehyde Dehydrogenase Family 1 Member L2 |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Mitochondrial 10-Formyltetrahydrofolate Dehydrogenase antibodyAnti-Mitochondrial 10-Fthfdh antibodyAnti-Mtfdh antibodyAnti-Aldehyde Dehydrogenase Family 1 Member L2 antibodyAnti-ALDH1L2 antibody |
Information sourced from Uniprot.org