Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ALDH1L2 (280-480) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:1000-1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ALDH1L2 |
Gene ID: |
160428 |
Uniprot ID: |
AL1L2_HUMAN |
Immunogen Region: |
280-480 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2). |
Immunogen Sequence: |
EPLEIKGAKKPGLVTKNGLV LFGNDGKALTVRNLQFEDGK MIPASQYFSTGETSVVELTA EEVKVAETIKVIWAGILSNV PIIEDSTDFFKSGASSMDVA RLVEEIRQKCGGLQLQNEDV YMATKFEGFIQKVVRKLRGE DQEVELVVDYISKEVNEIMV KMPYQCFINGQFTDADDGKT YDTINPTDGSTICKVSYASL A |
Tissue Specificity | Highly expressed in pancreas, heart, brain and skeletal muscle. |
Post Translational Modifications | Phosphopantetheinylation at Ser-375 by AASDHPPT is required for the formyltetrahydrofolate dehydrogenase activity. |
Function | Mitochondrial 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide. |
Protein Name | Mitochondrial 10-Formyltetrahydrofolate DehydrogenaseMitochondrial 10-FthfdhMtfdhAldehyde Dehydrogenase Family 1 Member L2 |
Database Links | Reactome: R-HSA-196757 |
Cellular Localisation | Mitochondrion |
Alternative Antibody Names | Anti-Mitochondrial 10-Formyltetrahydrofolate Dehydrogenase antibodyAnti-Mitochondrial 10-Fthfdh antibodyAnti-Mtfdh antibodyAnti-Aldehyde Dehydrogenase Family 1 Member L2 antibodyAnti-ALDH1L2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance