| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ALDH1L1 |
| Gene ID: | 10840 |
| Uniprot ID: | AL1L1_HUMAN |
| Immunogen Region: | 1-250 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALDH1L1 (NP_036322.2). |
| Immunogen Sequence: | MKIAVIGQSLFGQEVYCHLR KEGHEVVGVFTVPDKDGKAD PLGLEAEKDGVPVFKYSRWR AKGQALPDVVAKYQALGAEL NVLPFCSQFIPMEIISAPRH GSIIYHPSLLPRHRGASAIN WTLIHGDKKGGFSIFWADDG LDTGDLLLQKECEVLPDDTV STLYNRFLFPEGIKGMVQAV RLIAEGKAPRLPQPEEGATY EGIQKKETAKINWDQPAEAI HNWIRGNDKVPGAWTEACE |
| Tissue Specificity | Highly expressed in liver, pancreas and kidney. |
| Post Translational Modifications | Phosphopantetheinylation at Ser-354 by AASDHPPT is required for the formyltetrahydrofolate dehydrogenase activity. |
| Function | Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide. May also have an NADP(+)-dependent aldehyde dehydrogenase activity towards formaldehyde, acetaldehyde, propionaldehyde, and benzaldehyde. |
| Protein Name | Cytosolic 10-Formyltetrahydrofolate Dehydrogenase10-FthfdhFdhAldehyde Dehydrogenase Family 1 Member L1 |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Cytosolic 10-Formyltetrahydrofolate Dehydrogenase antibodyAnti-10-Fthfdh antibodyAnti-Fdh antibodyAnti-Aldehyde Dehydrogenase Family 1 Member L1 antibodyAnti-ALDH1L1 antibodyAnti-FTHFD antibody |
Information sourced from Uniprot.org