Anti-ALDH1B1 antibody (278-517) (STJ22580)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ALDH1B1 (278-517) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ALDH1B1 |
| Gene ID | 219 |
| Uniprot ID | AL1B1_HUMAN |
| Immunogen Region | 278-517 |
| Immunogen Sequence | NLKRVTLELGGKSPSIVLAD ADMEHAVEQCHEALFFNMGQ CCCAGSRTFVEESIYNEFLE RTVEKAKQRKVGNPFELDTQ QGPQVDKEQFERVLGYIQLG QKEGAKLLCGGERFGERGFF IKPTVFGGVQDDMRIAKEEI FGPVQPLFKFKKIEEVVERA NNTRYGLAAAVFTRDLDKAM YFTQALQAGTVWVNTYNIVT CHTPFGGFKESGNGRELGED GLKAYTEVKTVTIKVPQKN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3). |
Additional Info
| Tissue Specificity | Liver, testis and to a lesser extent in brain. |
| Function | ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
| Protein Name | Aldehyde Dehydrogenase X - MitochondrialAldehyde Dehydrogenase 5Aldehyde Dehydrogenase Family 1 Member B1 |
| Database Links | Reactome: R-HSA-71384Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Aldehyde Dehydrogenase X - Mitochondrial antibodyAnti-Aldehyde Dehydrogenase 5 antibodyAnti-Aldehyde Dehydrogenase Family 1 Member B1 antibodyAnti-ALDH1B1 antibodyAnti-ALDH5 antibodyAnti-ALDHX antibody |
Information sourced from Uniprot.org