Anti-AKR7A3 antibody (STJA0008217)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human AKR7A3
General Information
| Short Description | Rabbit polyclonal anti-Aflatoxin B1 aldehyde reductase member 3 for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKR7A3 |
| Gene ID | 22977 |
| Uniprot ID | ARK73_HUMAN |
| Immunogen | Synthesized peptide derived from human AKR7A3 |
| Specificity | This antibody detects endogenous levels of AKR7A3 at Human, Rat |
Additional Info
| Function | Catalyzes the NADPH-dependent reduction of various carbonyl-containing compounds, including aldehydes, ketones, and toxic products from cellular metabolism or environmental exposure. Can reduce the dialdehyde form of aflatoxin B1 (AFB1) into alcohol derivatives, via monoaldehydes intermediates. Can reduce the dialdehyde form of aflatoxin B1 (AFB1) into alcohol derivatives, via monoaldehydes intermediates, thus preventing the formation of protein adducts that contribute to AFB1-induced toxicity. |
| Protein Name | Aldo-Keto Reductase Family 7 Member A3Afb1 Aldehyde Reductase 2Afb1-Ar 2Aflatoxin B1 Aldehyde Reductase Member 3 |
| Database Links | Reactome: R-HSA-5423646 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Aldo-Keto Reductase Family 7 Member A3 antibodyAnti-Afb1 Aldehyde Reductase 2 antibodyAnti-Afb1-Ar 2 antibodyAnti-Aflatoxin B1 Aldehyde Reductase Member 3 antibodyAnti-AKR7A3 antibodyAnti-AFAR2 antibody |
Information sourced from Uniprot.org