STJ71467 (0. 03µg/ml) staining of A549 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-AKR1B10 antibody (C-Term) (STJ71467)

SKU:
STJ71467-100
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Goat polyclonal antibody anti-AKR1B10 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: Peptide ELISA: antibody detection limit dilution 1:8000.
WB: Approx 35kDa band observed in lysates of cell lines HEK293, A549 and HepG2 (calculated MW of 36.0kDa according to NP_064695.2). In transfected HEK293 transiently expressing AKR1B10 a ba
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: AKR1B10
Gene ID: 57016
Uniprot ID: AK1BA_HUMAN
Immunogen Region: C-Term
Accession Number: NP_064695.2
Immunogen Sequence: QSSHLEDYPFDAE
Function Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.
Protein Name Aldo-Keto Reductase Family 1 Member B10
Arl-1
Aldose Reductase-Like
Aldose Reductase-Related Protein
Arp
Harp
Small Intestine Reductase
Si Reductase
Database Links Reactome: R-HSA-975634
Cellular Localisation Lysosome
Secreted
Secreted Through A Lysosome-Mediated Non-Classical Pathway
Alternative Antibody Names Anti-Aldo-Keto Reductase Family 1 Member B10 antibody
Anti-Arl-1 antibody
Anti-Aldose Reductase-Like antibody
Anti-Aldose Reductase-Related Protein antibody
Anti-Arp antibody
Anti-Harp antibody
Anti-Small Intestine Reductase antibody
Anti-Si Reductase antibody
Anti-AKR1B10 antibody
Anti-AKR1B11 antibody

Information sourced from Uniprot.org

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