Anti-AKR1B10 antibody (124-174 aa) (STJ195042)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human AK1BA at the amino acid range 124-174
General Information
| Short Description | Rabbit polyclonal anti-Aldo-keto reductase family 1 member B10 (124-174 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AKR1B10 |
| Gene ID | 57016 |
| Uniprot ID | AK1BA_HUMAN |
| Immunogen | Synthesized peptide derived from the human AK1BA at the amino acid range 124-174 |
| Immunogen Region | 124-174 aa |
| Specificity | This antibody detects endogenous levels of AK1BA at Human |
Additional Info
| Function | Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose. |
| Protein Name | Aldo-Keto Reductase Family 1 Member B10Arl-1Aldose Reductase-LikeAldose Reductase-Related ProteinArpHarpSmall Intestine ReductaseSi Reductase |
| Database Links | Reactome: R-HSA-975634 |
| Cellular Localisation | LysosomeSecretedSecreted Through A Lysosome-Mediated Non-Classical Pathway |
| Alternative Antibody Names | Anti-Aldo-Keto Reductase Family 1 Member B10 antibodyAnti-Arl-1 antibodyAnti-Aldose Reductase-Like antibodyAnti-Aldose Reductase-Related Protein antibodyAnti-Arp antibodyAnti-Harp antibodyAnti-Small Intestine Reductase antibodyAnti-Si Reductase antibodyAnti-AKR1B10 antibodyAnti-AKR1B11 antibody |
Information sourced from Uniprot.org