Anti-AKR1B10 antibody (124-174 aa) (STJ195042)

SKU:
STJ195042
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Aldo-keto reductase family 1 member B10 (124-174 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:AKR1B10
Gene ID:57016
Uniprot ID:AK1BA_HUMAN
Immunogen:Synthesized peptide derived from the human AK1BA at the amino acid range 124-174
Immunogen Region:124-174 aa
Specificity:This antibody detects endogenous levels of AK1BA at Human
Function Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.
Protein Name Aldo-Keto Reductase Family 1 Member B10
Arl-1
Aldose Reductase-Like
Aldose Reductase-Related Protein
Arp
Harp
Small Intestine Reductase
Si Reductase
Database Links Reactome: R-HSA-975634
Cellular Localisation Lysosome
Secreted
Secreted Through A Lysosome-Mediated Non-Classical Pathway
Alternative Antibody Names Anti-Aldo-Keto Reductase Family 1 Member B10 antibody
Anti-Arl-1 antibody
Anti-Aldose Reductase-Like antibody
Anti-Aldose Reductase-Related Protein antibody
Anti-Arp antibody
Anti-Harp antibody
Anti-Small Intestine Reductase antibody
Anti-Si Reductase antibody
Anti-AKR1B10 antibody
Anti-AKR1B11 antibody

Information sourced from Uniprot.org