| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AK3 (1-227) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AK3 |
| Gene ID: |
50808 |
| Uniprot ID: |
KAD3_HUMAN |
| Immunogen Region: |
1-227 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human AK3 (NP_057366.2). |
| Immunogen Sequence: |
MGASARLLRAVIMGAPGSGK GTVSSRITTHFELKHLSSGD LLRDNMLRGTEIGVLAKAFI DQGKLIPDDVMTRLALHELK NLTQYSWLLDGFPRTLPQAE ALDRAYQIDTVINLNVPFEV IKQRLTARWIHPASGRVYNI EFNPPKTVGIDDLTGEPLIQ REDDKPETVIKRLKAYEDQT KPVLEYYQKKGVLETFSGTE TNKIWPYVYAFLQTKVPQRS QKASVTP |
| Tissue Specificity | Highly expressed in heart, skeletal muscle and liver, moderately expressed in pancreas and kidney, and weakly expressed in placenta, brain and lung. |
| Function | Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. |
| Protein Name | Gtp -Amp Phosphotransferase Ak3 - MitochondrialAdenylate Kinase 3Ak 3Adenylate Kinase 3 Alpha-Like 1 |
| Database Links | Reactome: R-HSA-983231 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Gtp -Amp Phosphotransferase Ak3 - Mitochondrial antibodyAnti-Adenylate Kinase 3 antibodyAnti-Ak 3 antibodyAnti-Adenylate Kinase 3 Alpha-Like 1 antibodyAnti-AK3 antibodyAnti-AK3L1 antibodyAnti-AK6 antibodyAnti-AKL3L antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CHCHD3 knockout (KO) 293T cells, using [KO Validated] CHCHD3 Rabbit polyclonal antibody (STJ11100835) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89770/358242/STJ11100835_1__03090.1713122575.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CHCHD3 knockout (KO) 293T cells, using [KO Validated] CHCHD3 Rabbit polyclonal antibody (STJ11100835) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.")