Host: | Goat |
Applications: | Pep-ELISA |
Reactivity: | Human/Mouse/Rat/Dog/Cow |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-AIFM3 (Internal) is suitable for use in ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments in Human Colon, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | AIFM3 |
Gene ID: | 150209 |
Uniprot ID: | AIFM3_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_653305.1; NP_001018070.1; NP_001139760.1 |
Specificity: | This antibody is expected to recognize all isoforms (NP_653305.1; NP_001018070.1, NP_001139760.1). |
Immunogen Sequence: | TARHFHTEERLSTPH |
Function | Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. |
Protein Name | Apoptosis-Inducing Factor 3Apoptosis-Inducing Factor-Like Protein |
Cellular Localisation | MitochondrionDoes Not Translocate To The Nucleus Upon Induction Of Apoptosis |
Alternative Antibody Names | Anti-Apoptosis-Inducing Factor 3 antibodyAnti-Apoptosis-Inducing Factor-Like Protein antibodyAnti-AIFM3 antibodyAnti-AIFL antibody |
Information sourced from Uniprot.org