| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Mouse/Rat/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-AIFM3 (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Preliminary experiments in Human Colon, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | AIFM3 |
| Gene ID: | 150209 |
| Uniprot ID: | AIFM3_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_653305.1; NP_001018070.1; NP_001139760.1 |
| Specificity: | This antibody is expected to recognize all isoforms (NP_653305.1; NP_001018070.1, NP_001139760.1). |
| Immunogen Sequence: | TARHFHTEERLSTPH |
| Function | Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. |
| Protein Name | Apoptosis-Inducing Factor 3Apoptosis-Inducing Factor-Like Protein |
| Cellular Localisation | MitochondrionDoes Not Translocate To The Nucleus Upon Induction Of Apoptosis |
| Alternative Antibody Names | Anti-Apoptosis-Inducing Factor 3 antibodyAnti-Apoptosis-Inducing Factor-Like Protein antibodyAnti-AIFM3 antibodyAnti-AIFL antibody |
Information sourced from Uniprot.org
