| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-AHSG (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 60kDa band observed in Human albunin-depleted Serum lysates (calculated MW of 39.3kDa according to NP_001613.2). This molecular weight is routinely observed by other sources. R |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | AHSG |
| Gene ID: | 197 |
| Uniprot ID: | FETUA_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001613.2 |
| Immunogen Sequence: | QPEGANEAVPTP |
| Post Translational Modifications | Phosphorylated by FAM20C in the extracellular medium. O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4.N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor). |
| Function | Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. |
| Protein Name | Alpha-2-Hs-GlycoproteinAlpha-2-Z-GlobulinBa-Alpha-2-GlycoproteinFetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-6798695Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-2-Hs-Glycoprotein antibodyAnti-Alpha-2-Z-Globulin antibodyAnti-Ba-Alpha-2-Glycoprotein antibodyAnti-Fetuin-A Cleaved Into - Alpha-2-Hs-Glycoprotein Chain A - Alpha-2-Hs-Glycoprotein Chain B antibodyAnti-AHSG antibodyAnti-FETUA antibodyAnti-PRO2743 antibody |
Information sourced from Uniprot.org