| Function | Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. |
| Protein Name | JouberinAbelson Helper Integration Site 1 Protein HomologAhi-1 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyCell JunctionAdherens JunctionMicrotubule Organizing CenterCentrosomeCentrioleIn The Retinal Photoreceptor Cell LayerLocalizes At The Connecting Cilium |
| Alternative Antibody Names | Anti-Jouberin antibodyAnti-Abelson Helper Integration Site 1 Protein Homolog antibodyAnti-Ahi-1 antibodyAnti-AHI1 antibody |
Information sourced from Uniprot.org
