| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Jouberin is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AHI1 |
| Gene ID: |
54806 |
| Uniprot ID: |
AHI1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of AHI1 at Human, Rat |
| Immunogen: |
Synthesized peptide derived from human AHI1 |
| Function | Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. |
| Protein Name | JouberinAbelson Helper Integration Site 1 Protein HomologAhi-1 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | CytoplasmCytoskeletonCilium Basal BodyCell JunctionAdherens JunctionMicrotubule Organizing CenterCentrosomeCentrioleIn The Retinal Photoreceptor Cell LayerLocalizes At The Connecting Cilium |
| Alternative Antibody Names | Anti-Jouberin antibodyAnti-Abelson Helper Integration Site 1 Protein Homolog antibodyAnti-Ahi-1 antibodyAnti-AHI1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
