Anti-AGXT2 antibody (340-420 aa) (STJ190527)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 340-420
General Information
| Short Description | Rabbit polyclonal anti-Alanine--glyoxylate aminotransferase 2, mitochondrial-3-amino-2-methylpropionate--pyruvate transaminase (340-420 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AGXT2 |
| Gene ID | 64902 |
| Uniprot ID | AGT2_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 340-420 |
| Immunogen Region | 340-420 aa |
| Specificity | AGT2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Multifunctional aminotransferase with a broad substrate specificity. Catalyzes the conversion of glyoxylate to glycine using alanine as the amino donor. Catalyzes metabolism of not L- but the D-isomer of D-beta-aminoisobutyric acid to generate 2-methyl-3-oxopropanoate and alanine. Catalyzes the transfer of the amino group from beta-alanine to pyruvate to yield L-alanine and 3-oxopropanoate. Can metabolize NG-monomethyl-L-arginine (NMMA), asymmetric NG,NG-dimethyl-L-arginine (ADMA) and symmetric NG,N'G-dimethyl-L-arginine (SDMA). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure. |
| Protein Name | Alanine--Glyoxylate Aminotransferase 2 - MitochondrialAgt 2(R-3-Amino-2-Methylpropionate--Pyruvate TransaminaseBeta-Alaat IiBeta-Alanine-Pyruvate AminotransferaseD-3-Aminoisobutyrate-Pyruvate AminotransferaseD-AibatD-Beta-Aminoisobutyrate-Pyruvate Aminotransferase |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Alanine--Glyoxylate Aminotransferase 2 - Mitochondrial antibodyAnti-Agt 2 antibodyAnti-(R-3-Amino-2-Methylpropionate--Pyruvate Transaminase antibodyAnti-Beta-Alaat Ii antibodyAnti-Beta-Alanine-Pyruvate Aminotransferase antibodyAnti-D-3-Aminoisobutyrate-Pyruvate Aminotransferase antibodyAnti-D-Aibat antibodyAnti-D-Beta-Aminoisobutyrate-Pyruvate Aminotransferase antibodyAnti-AGXT2 antibodyAnti-AGT2 antibody |
Information sourced from Uniprot.org