Host: | Goat |
Applications: | Pep-ELISA/IF/FC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Goat polyclonal antibody anti-AGXT/AGT (Internal) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:2000. IF: Strong expression of the protein seen in the vesicles of HeLa and HepG2 cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of HepG2 cells. Recommended concentratio |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Gene Symbol: | AGXT |
Gene ID: | 189 |
Uniprot ID: | AGT1_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_000021.1 |
Immunogen Sequence: | DKAKKKMYSRK |
Function | Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification. Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism. |
Protein Name | Alanine--Glyoxylate Aminotransferase Agt Serine--Pyruvate Aminotransferase Spt |
Database Links | Reactome: R-HSA-389661 Reactome: R-HSA-9033241 |
Cellular Localisation | Peroxisome |
Alternative Antibody Names | Anti-Alanine--Glyoxylate Aminotransferase antibody Anti-Agt antibody Anti-Serine--Pyruvate Aminotransferase antibody Anti-Spt antibody Anti-AGXT antibody Anti-AGT1 antibody Anti-SPAT antibody |
Information sourced from Uniprot.org