Anti-AGTR2 Receptor antibody (STJA0037550)

SKU:
STJA0037550
£133.50 - £281.50
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Host: Rabbit
Applications: WB/IP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-AGTR2 Receptor for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification: Affinity Purified
Dilution Range: WB-1:1000-1:5000
IP-1:10-1:100
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: AGTR2
Gene ID: 186
Uniprot ID: AGTR2_HUMAN
Immunogen: Peptide
Tissue Specificity In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine.
Function Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
Protein Name Type-2 Angiotensin Ii Receptor
Angiotensin Ii Type-2 Receptor
At2 Receptor
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Type-2 Angiotensin Ii Receptor antibody
Anti-Angiotensin Ii Type-2 Receptor antibody
Anti-At2 Receptor antibody
Anti-AGTR2 antibody

Information sourced from Uniprot.org

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