| Host: | Mouse |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-AFP is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 5108 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Purification: | Purity accurate to greater than or equal to 95% |
| Concentration: | 5.0 mg/ml (+/-10 %) |
| Storage Instruction: | 24 months from manufacturing at 2°C. Temperature analysis:-70 °C, 21 days N/D-20 °C, 21 days N/D +4 °C, 21 days N/D +35 °C, 7 days N/D +35 °C, 21 days N/D +45 °C, 3 days N/D +45 °C, 7 days N/D. Shelf life stability testing at 2–8 °C in the product bu |
| Determination Method: | Radioimmunoassay (RIA) |
| Immunoreactivity: | 80–120 % compared to the reference sample in an FIA test |
| Gene Symbol: | AFP |
| Gene ID: | 174 |
| Uniprot ID: | FETA_HUMAN |
| Immunogen: | human Alpha1-fetoprotein |
| Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
| Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
| Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Protein Name | Alpha-FetoproteinAlpha-1-FetoproteinAlpha-Fetoglobulin |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-Fetoprotein antibodyAnti-Alpha-1-Fetoprotein antibodyAnti-Alpha-Fetoglobulin antibodyAnti-AFP antibodyAnti-HPAFP antibody |
Information sourced from Uniprot.org