• STJ72590 (0. 3µg/ml) staining of Human Cerebral Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-AES antibody (N-Term) (STJ72590)

SKU:
STJ72590-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-AES (N-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.3-1µg/ml
IHC-3.75µg/ml
ELISA-antibody detection limit dilution 1:64000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: TLE5
Gene ID: 166
Uniprot ID: TLE5_HUMAN
Immunogen Region: N-Term
Accession Number: NP_945320.1; NP_001121.2; NP_945321.1
Specificity: This antibody is expected to recognize all reported isoforms (NP_945320.1; NP_001121.2; NP_945321.1).
Immunogen Sequence: SHLPQQLKFTTSD
Post Translational Modifications Ubiquitinated by XIAP/BIRC4.
Function Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.
Protein Name Tle Family Member 5
Amino-Terminal Enhancer Of Split
Amino Enhancer Of Split
Gp130-Associated Protein Gam
Grg-5
Groucho-Related Protein 5
Protein Esp1
Protein Grg
Tle Family Member 5 - Transcriptional Modulator
Database Links Reactome: R-HSA-4641265
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Tle Family Member 5 antibody
Anti-Amino-Terminal Enhancer Of Split antibody
Anti-Amino Enhancer Of Split antibody
Anti-Gp130-Associated Protein Gam antibody
Anti-Grg-5 antibody
Anti-Groucho-Related Protein 5 antibody
Anti-Protein Esp1 antibody
Anti-Protein Grg antibody
Anti-Tle Family Member 5 - Transcriptional Modulator antibody
Anti-TLE5 antibody
Anti-AES antibody
Anti-GRG antibody
Anti-GRG5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance