Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Adipocyte enhancer-binding protein 1 (780-810 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | AEBP1 |
Gene ID: | 165 |
Uniprot ID: | AEBP1_HUMAN |
Immunogen Region: | 780-810 aa |
Specificity: | AEBP1 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein at the amino acid range 780-810 |
Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
Alternative Antibody Names | Anti-Adipocyte Enhancer-Binding Protein 1 antibodyAnti-Ae-Binding Protein 1 antibodyAnti-Aortic Carboxypeptidase-Like Protein antibodyAnti-AEBP1 antibodyAnti-ACLP antibody |
Information sourced from Uniprot.org