| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adipocyte enhancer-binding protein 1 (780-810 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AEBP1 |
| Gene ID: |
165 |
| Uniprot ID: |
AEBP1_HUMAN |
| Immunogen Region: |
780-810 aa |
| Specificity: |
AEBP1 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from part of the human protein at the amino acid range 780-810 |
| Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
| Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Adipocyte Enhancer-Binding Protein 1 antibodyAnti-Ae-Binding Protein 1 antibodyAnti-Aortic Carboxypeptidase-Like Protein antibodyAnti-AEBP1 antibodyAnti-ACLP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
