• STJ73735 (6µg/ml) staining of paraffin embedded Human Heart. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.
  • STJ73735 Negative Control showing staining of paraffin embedded Human Heart, with no primary antibody.
  • STJ73735 Immunofluorescence analysis of paraformaldehyde fixed HeLa cells, permeabilized with 0. 15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml) , showing membrane and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).

Anti-ADRB1 antibody (Internal) (STJ73735)

SKU:
STJ73735-100

£303.50
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Host: Goat
Applications: Pep-ELISA/IHC/IF
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ADRB1 (Internal) is suitable for use in ELISA, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: IHC-4-6µg/ml
ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ADRB1
Gene ID: 153
Uniprot ID: ADRB1_HUMAN
Immunogen Region: Internal
Accession Number: NP_000675.1
Immunogen Sequence: ESDEARRCYNDPK
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Involved in the regulation of sleep/wake behaviors.
Protein Name Beta-1 Adrenergic Receptor
Beta-1 Adrenoreceptor
Beta-1 Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-418555
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Early Endosome
Colocalizes With Rapgef2 At The Plasma Membrane
Localized At The Plasma Membrane
Found In The Golgi Upon Gopc Overexpression
Alternative Antibody Names Anti-Beta-1 Adrenergic Receptor antibody
Anti-Beta-1 Adrenoreceptor antibody
Anti-Beta-1 Adrenoceptor antibody
Anti-ADRB1 antibody
Anti-ADRB1R antibody
Anti-B1AR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance