| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADRA2A |
| Gene ID: | 150 |
| Uniprot ID: | ADA2A_HUMAN |
| Immunogen Region: | 240-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2A (NP_000672.3). |
| Immunogen Sequence: | RRTRVPPSRRGPDAVAAPPG GTERRPNGLGPERSAGPGGA EAEPLPTQLNGAPGEPAPAG PRDTDALDLEESSSSDHAER PPGPRRPERGPRGKGKARAS QVKPGDSLPRRGPGATGIGT PAAGPGEERVGAAKASRWRG R |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. |
| Protein Name | Alpha-2a Adrenergic ReceptorAlpha-2 Adrenergic Receptor Subtype C10Alpha-2a AdrenoreceptorAlpha-2a AdrenoceptorAlpha-2aar |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-392023Reactome: R-HSA-400042Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-2a Adrenergic Receptor antibodyAnti-Alpha-2 Adrenergic Receptor Subtype C10 antibodyAnti-Alpha-2a Adrenoreceptor antibodyAnti-Alpha-2a Adrenoceptor antibodyAnti-Alpha-2aar antibodyAnti-ADRA2A antibodyAnti-ADRA2R antibodyAnti-ADRAR antibody |
Information sourced from Uniprot.org
