| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADRA2A (240-380) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADRA2A |
| Gene ID: |
150 |
| Uniprot ID: |
ADA2A_HUMAN |
| Immunogen Region: |
240-380 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human ADRA2A (NP_000672.3). |
| Immunogen Sequence: |
RRTRVPPSRRGPDAVAAPPG GTERRPNGLGPERSAGPGGA EAEPLPTQLNGAPGEPAPAG PRDTDALDLEESSSSDHAER PPGPRRPERGPRGKGKARAS QVKPGDSLPRRGPGATGIGT PAAGPGEERVGAAKASRWRG R |
| Function | Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. |
| Protein Name | Alpha-2a Adrenergic ReceptorAlpha-2 Adrenergic Receptor Subtype C10Alpha-2a AdrenoreceptorAlpha-2a AdrenoceptorAlpha-2aar |
| Database Links | Reactome: R-HSA-390696Reactome: R-HSA-392023Reactome: R-HSA-400042Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-2a Adrenergic Receptor antibodyAnti-Alpha-2 Adrenergic Receptor Subtype C10 antibodyAnti-Alpha-2a Adrenoreceptor antibodyAnti-Alpha-2a Adrenoceptor antibodyAnti-Alpha-2aar antibodyAnti-ADRA2A antibodyAnti-ADRA2R antibodyAnti-ADRAR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
