| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADORA2A |
| Gene ID: | 135 |
| Uniprot ID: | AA2AR_HUMAN |
| Immunogen Region: | 300-400 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ADORA2A (NP_000666.2). |
| Immunogen Sequence: | RKIIRSHVLRQQEPFKAAGT SARVLAAHGSDGEQVSLRLN GHPPGVWANGSAPHPERRPN GYALGLVSGGSAQESQGNTG LPDVELLSHELKGVCPEPPG L |
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP4.leading to stabilization and expression at the cell surface. |
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Adenosine Receptor A2a |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-417973Reactome: R-HSA-418555Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gas2l2 At Neuronal Processes |
| Alternative Antibody Names | Anti-Adenosine Receptor A2a antibodyAnti-ADORA2A antibodyAnti-ADORA2 antibody |
Information sourced from Uniprot.org