| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Adiponectin receptor protein 2 (62-112 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADIPOR2 |
| Gene ID: | 79602 |
| Uniprot ID: | PAQR2_HUMAN |
| Immunogen Region: | 62-112 aa |
| Specificity: | This antibody detects endogenous levels of ADR2 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human ADR2 at the amino acid range 62-112 |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. |
| Protein Name | Adiponectin Receptor Protein 2Progestin And Adipoq Receptor Family Member 2Progestin And Adipoq Receptor Family Member Ii |
| Database Links | Reactome: R-HSA-163680 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles |
| Alternative Antibody Names | Anti-Adiponectin Receptor Protein 2 antibodyAnti-Progestin And Adipoq Receptor Family Member 2 antibodyAnti-Progestin And Adipoq Receptor Family Member Ii antibodyAnti-ADIPOR2 antibodyAnti-PAQR2 antibody |
Information sourced from Uniprot.org
