Western blot analysis of lysates from Rat skeletal muscle, using ADIPOR2 Rabbit polyclonal antibody (STJ114650) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-ADIPOR2 antibody (1-147) (STJ114650)

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STJ114650
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADIPOR2
Gene ID: 79602
Uniprot ID: PAQR2_HUMAN
Immunogen Region: 1-147
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human ADIPOR2 (NP_078827.2).
Immunogen Sequence: MNEPTENRLGCSRTPEPDIR LRKGHQLDGTRRGDNDSHQG DLEPILEASVLSSHHKKSSE EHEYSDEAPQEDEGFMGMSP LLQAHHAMEKMEEFVCKVWE GRWRVIPHDVLPDWLKDNDF LLHGHRPPMPSFRACFKSIF RIHTETG
Tissue Specificity Ubiquitous. Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung.
Function Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels.
Protein Name Adiponectin Receptor Protein 2
Progestin And Adipoq Receptor Family Member 2
Progestin And Adipoq Receptor Family Member Ii
Database Links Reactome: R-HSA-163680
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Localized To The Cell Membrane And Intracellular Organelles
Alternative Antibody Names Anti-Adiponectin Receptor Protein 2 antibody
Anti-Progestin And Adipoq Receptor Family Member 2 antibody
Anti-Progestin And Adipoq Receptor Family Member Ii antibody
Anti-ADIPOR2 antibody
Anti-PAQR2 antibody

Information sourced from Uniprot.org

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