Anti-ADIPOR2 antibody (1-147) (STJ114650)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal ADIPOR2 (1-147) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADIPOR2 |
| Gene ID | 79602 |
| Uniprot ID | PAQR2_HUMAN |
| Immunogen Region | 1-147 |
| Immunogen Sequence | MNEPTENRLGCSRTPEPDIR LRKGHQLDGTRRGDNDSHQG DLEPILEASVLSSHHKKSSE EHEYSDEAPQEDEGFMGMSP LLQAHHAMEKMEEFVCKVWE GRWRVIPHDVLPDWLKDNDF LLHGHRPPMPSFRACFKSIF RIHTETG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human ADIPOR2 (NP_078827.2). |
Additional Info
| Tissue Specificity | Ubiquitous. Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung. |
| Function | Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism. Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels. |
| Protein Name | Adiponectin Receptor Protein 2Progestin And Adipoq Receptor Family Member 2Progestin And Adipoq Receptor Family Member Ii |
| Database Links | Reactome: R-HSA-163680 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinLocalized To The Cell Membrane And Intracellular Organelles |
| Alternative Antibody Names | Anti-Adiponectin Receptor Protein 2 antibodyAnti-Progestin And Adipoq Receptor Family Member 2 antibodyAnti-Progestin And Adipoq Receptor Family Member Ii antibodyAnti-ADIPOR2 antibodyAnti-PAQR2 antibody |
Information sourced from Uniprot.org