Anti-ADH5 antibody [4D4] (STJA0032615)

SKU:
STJA0032615
£224.50 - £308.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Mouse monoclonal anti-ADH5 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P
Host:Mouse
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :4D4
Isotype:IgG1
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
Formulation:Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:ADH5
Gene ID:128
Uniprot ID:ADHX_HUMAN
Immunogen:Purified recombinant human ADH5 protein fragments expressed in E.coli.
Function Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol. Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage. Also acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation.
Protein Name Alcohol Dehydrogenase Class-3
Alcohol Dehydrogenase 5
Alcohol Dehydrogenase Class Chi Chain
Alcohol Dehydrogenase Class-Iii
Glutathione-Dependent Formaldehyde Dehydrogenase
Faldh
Fdh
Gsh-Fdh
S-(Hydroxymethylglutathione Dehydrogenase
Database Links Reactome: R-HSA-71384
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Alcohol Dehydrogenase Class-3 antibody
Anti-Alcohol Dehydrogenase 5 antibody
Anti-Alcohol Dehydrogenase Class Chi Chain antibody
Anti-Alcohol Dehydrogenase Class-Iii antibody
Anti-Glutathione-Dependent Formaldehyde Dehydrogenase antibody
Anti-Faldh antibody
Anti-Fdh antibody
Anti-Gsh-Fdh antibody
Anti-S-(Hydroxymethylglutathione Dehydrogenase antibody
Anti-ADH5 antibody
Anti-ADHX antibody
Anti-FDH antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0042308 Anti-Vinculin antibody [4D4] {EF594} (STJA0042308) Mouse Monoclonal Human/Mouse/Rat IF
STJA0037750 Anti-KMT6 antibody [R07-4D4] (STJA0037750) Rabbit Monoclonal Human IHC-P
STJA0042307 Anti-Vinculin antibody [4D4] {EF647} (STJA0042307) Mouse Monoclonal Human FC
STJA0042305 Anti-Vinculin antibody [4D4] {HRP} (STJA0042305) Mouse Monoclonal Human/Mouse/Rat WB
STJA0034474 Anti-ITPA antibody [R01-4D4] (STJA0034474) Rabbit Monoclonal Human WB/IHC-P

Related Products

!