| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADH4 |
| Gene ID: | 127 |
| Uniprot ID: | ADH4_HUMAN |
| Immunogen Region: | 1-380 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human ADH4 (NP_000661.2). |
| Immunogen Sequence: | MGTKGKVIKCKAAIAWEAGK PLCIEEVEVAPPKAHEVRIQ IIATSLCHTDATVIDSKFEG LAFPVIVGHEAAGIVESIGP GVTNVKPGDKVIPLYAPLCR KCKFCLSPLTNLCGKISNLK SPASDQQLMEDKTSRFTCKG KPVYHFFGTSTFSQYTVVSD INLAKIDDDANLERVCLLGC GFSTGYGAAINNAKVTPGST CAVFGLGGVGLSAVMGCKAA GASRIIGIDINSEKFVKAK |
| Function | Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh4Alcohol Dehydrogenase 2Alcohol Dehydrogenase 4Alcohol Dehydrogenase Class Ii Pi Chain |
| Database Links | Reactome: R-HSA-5365859Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-All-Trans-Retinol Dehydrogenase Nad(+ Adh4 antibodyAnti-Alcohol Dehydrogenase 2 antibodyAnti-Alcohol Dehydrogenase 4 antibodyAnti-Alcohol Dehydrogenase Class Ii Pi Chain antibodyAnti-ADH4 antibodyAnti-ADH2 antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89136/357585/STJ11100066_1__93634.1713121719.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and PAK2 knockout (KO) HeLa cells, using [KO Validated] PAK2 Rabbit polyclonal antibody (STJ11100066) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.")
