| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Adgre1 |
| Gene ID: | 13733 |
| Uniprot ID: | AGRE1_MOUSE |
| Immunogen Region: | 367-931 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 367-645 of mouse F4/80 (NP_034260.1). |
| Immunogen Sequence: | KRILFKCKEDLILQSEQIQQ CQAVQGRDLGYASFCTLVNA TFTILDNTCENKSAPVSLQS AATSVSLVLEQATTWFELSK EETSTLGTILLETVESTMLA ALLIPSGNASQMIQTEYLDI ESKVINEECKENESINLAAR GDKMNVGCFIIKESVSTGAP GVAFVSFAHMESVLNERFFE DGQSFRKLRMNSRVVGGTVT GEKKEDFSKPIIYTLQHIQP KQKSERPICVSWNTDVEDG |
| Tissue Specificity | In macrophages.but absent from those which are localized within T-cell areas of lymph nodes and spleen. Low level of expression on blood monocytes. |
| Function | Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. |
| Protein Name | Adhesion G Protein-Coupled Receptor E1Cell Surface Glycoprotein F4/80Egf-Like Module Receptor 1Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1Emr1 Hormone Receptor |
| Database Links | Reactome: R-MMU-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E1 antibodyAnti-Cell Surface Glycoprotein F4/80 antibodyAnti-Egf-Like Module Receptor 1 antibodyAnti-Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 1 antibodyAnti-Emr1 Hormone Receptor antibodyAnti-Adgre1 antibodyAnti-Emr1 antibodyAnti-Gpf480 antibody |
Information sourced from Uniprot.org
![Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000130) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/144983/291652/STJA0000130_1__14933.1631205435.jpg?c=1 "Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000130) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.")
![Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000129) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/144982/291651/STJA0000129_1__11143.1631205434.jpg?c=1 "Mouse abdominal macrophages elicited by starch broth were stained with Anti-F4/80 antibody (STJA0000129) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained macrophages (blank black histogram) were used as control.")
