Host: |
Rabbit |
Applications: |
IHC/IF/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Adhesion G protein-coupled receptor B2 (91-140 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ADGRB2 |
Gene ID: |
576 |
Uniprot ID: |
AGRB2_HUMAN |
Immunogen Region: |
91-140 aa |
Specificity: |
BAI-2 Polyclonal Antibody detects endogenous levels of BAI-2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human BAI2 at the amino acid range 91-140 |
Post Translational Modifications | Autoproteolytically processed at the GPS domain.this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment. Glycosylated. |
Function | Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition. |
Protein Name | Adhesion G Protein-Coupled Receptor B2Brain-Specific Angiogenesis Inhibitor 2 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinSecreted |
Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor B2 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 2 antibodyAnti-ADGRB2 antibodyAnti-BAI2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance