| Host: |
Rabbit |
| Applications: |
ELISA/WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adenylate cyclase 1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
FITC |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.72 µg/µl |
| Dilution Range: |
WB: 1:500DB: 1:10, 000ELISA: 1:10, 000 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Adcy1 |
| Gene ID: |
432530 |
| Uniprot ID: |
ADCY1_MOUSE |
| Immunogen Region: |
C-Term |
| Immunogen: |
Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein. |
| Tissue Specificity | Expressed throughout inner ear development. |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. |
| Protein Name | Adenylate Cyclase Type 1Atp Pyrophosphate-Lyase 1Adenylate Cyclase Type IAdenylyl Cyclase 1Ca(2+/Calmodulin-Activated Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-163615Reactome: -MMU-170660Reactome: -MMU-170670Reactome: -MMU-418597Reactome: -MMU-5610787 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmMembrane RaftExpressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea VestibuleAs Well As To The Cochlear Hair Cell Nuclei And Stereocilia| |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 1 antibodyAnti-Atp Pyrophosphate-Lyase 1 antibodyAnti-Adenylate Cyclase Type I antibodyAnti-Adenylyl Cyclase 1 antibodyAnti-Ca(2+/Calmodulin-Activated Adenylyl Cyclase antibodyAnti-Adcy1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
