Anti-Adenylate cyclase 1 antibody (C-Term) {Biotin} (STJ502062)

SKU:
STJ502062-100
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Short Description :Rabbit polyclonal antibody anti-Adenylate cyclase 1 (C-Term) is suitable for use in ELISA and Western Blot research applications.
Applications:ELISA/WB
Host:Rabbit
Reactivity:Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Biotin
Concentration:0.72 µg/µl
Purification:Affinity Purified
Dilution Range:WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Formulation:Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Storage Instruction:Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol:Adcy1
Gene ID:432530
Uniprot ID:ADCY1_MOUSE
Immunogen:Synthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouse Adenylyl Cyclase 1 protein.
Immunogen Region:C-Term
Tissue Specificity Expressed throughout inner ear development.
Post Translational Modifications N-glycosylated.
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.
Protein Name Adenylate Cyclase Type 1
Atp Pyrophosphate-Lyase 1
Adenylate Cyclase Type I
Adenylyl Cyclase 1
Ca(2+/Calmodulin-Activated Adenylyl Cyclase
Database Links Reactome: R-MMU-163615
Reactome: -MMU-170660
Reactome: -MMU-170670
Reactome: -MMU-418597
Reactome: -MMU-5610787
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Cell Membrane
Cytoplasm
Membrane Raft
Expressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea Vestibule
As Well As To The Cochlear Hair Cell Nuclei And Stereocilia|
Alternative Antibody Names Anti-Adenylate Cyclase Type 1 antibody
Anti-Atp Pyrophosphate-Lyase 1 antibody
Anti-Adenylate Cyclase Type I antibody
Anti-Adenylyl Cyclase 1 antibody
Anti-Ca(2+/Calmodulin-Activated Adenylyl Cyclase antibody
Anti-Adcy1 antibody

Information sourced from Uniprot.org