• Western blot analysis of various lysates using ADCY10 Rabbit polyclonal antibody (STJ11100427) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.

Anti-ADCY10 antibody (1-290) (STJ11100427)

SKU:
STJ11100427

$151.88 - $705.38
Shipping:
Free Shipping
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ADCY10 (1-290) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADCY10
Gene ID: 55811
Uniprot ID: ADCYA_HUMAN
Immunogen Region: 1-290
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human ADCY10 (NP_060887.2).
Immunogen Sequence: MNTPKEEFQDWPIVRIAAHL PDLIVYGHFSPERPFMDYFD GVLMFVDISGFTAMTEKFSS AMYMDRGAEQLVEILNYHIS AIVEKVLIFGGDILKFAGDA LLALWRVERKQLKNIITVVI KCSLEIHGLFETQEWEEGLD IRVKIGLAAGHISMLVFGDE THSHFLVIGQAVDDVRLAQN MAQMNDVILSPNCWQLCDRS MIEIESVPDQRAVKVNFLKP PPNFNFDEFFTKCTTFMHY
Tissue Specificity Detected in airway epithelial cells and testis (at protein level). Weakly expressed in multiple tissues. Expressed in brain, heart, kidney, liver, lung, pancreas, peripheral blood leukocytes, placenta, skeletal muscle, stomach, thymus, airway epithelial cells, duodenum, jejunum and ileum. Very low level of expression in bone.
Post Translational Modifications Cleavage may occur to generate the active 48 kDa form.
Function Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation.
Protein Name Adenylate Cyclase Type 10
Ah-Related Protein
Adenylate Cyclase Homolog
Germ Cell Soluble Adenylyl Cyclase
Hsac
Sac
Testicular Soluble Adenylyl Cyclase
Database Links Reactome: R-HSA-5610787
Cellular Localisation Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cytoplasm
Cytoskeleton
Perinuclear Region
Nucleus
Cell Projection
Cilium
Mitochondrion
Distributed To Subcellular Compartments Containing Camp Targets
Found As A Plasma Membrane-Associated Protein
Protein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin
Alternative Antibody Names Anti-Adenylate Cyclase Type 10 antibody
Anti-Ah-Related Protein antibody
Anti-Adenylate Cyclase Homolog antibody
Anti-Germ Cell Soluble Adenylyl Cyclase antibody
Anti-Hsac antibody
Anti-Sac antibody
Anti-Testicular Soluble Adenylyl Cyclase antibody
Anti-ADCY10 antibody
Anti-SAC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance