| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Adenylate cyclase type 1/calmodulin-activated adenylyl cyclase (231-280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADCY1 |
| Gene ID: | 107 |
| Uniprot ID: | ADCY1_HUMAN |
| Immunogen Region: | 231-280 aa |
| Specificity: | A Cyclase I Polyclonal Antibody detects endogenous levels of A Cyclase I protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ADCY1 at the amino acid range 231-280 |
| Post Translational Modifications | N-glycosylated. |
| Function | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina. |
| Protein Name | Adenylate Cyclase Type 1Atp Pyrophosphate-Lyase 1Adenylate Cyclase Type IAdenylyl Cyclase 1Ca(2+/Calmodulin-Activated Adenylyl Cyclase |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-442720Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell MembraneCytoplasmMembrane RaftExpressed In The Cytoplasm Of Supporting Cells And Hair Cells Of The Cochlea VestibuleAs Well As To The Cochlear Hair Cell Nuclei And Stereocilia |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 1 antibodyAnti-Atp Pyrophosphate-Lyase 1 antibodyAnti-Adenylate Cyclase Type I antibodyAnti-Adenylyl Cyclase 1 antibodyAnti-Ca(2+/Calmodulin-Activated Adenylyl Cyclase antibodyAnti-ADCY1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
