Anti-ADAM22 antibody (Cytoplasmic Domain) (STJ13100027)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from cytoplasmic domain of mouse ADAM22 (Metalloproteinase-disintegrin ADAM22-3) conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-ADAM22 (Cytoplasmic Domain) for use in IHC and WB in Mouse and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1: 300 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20ยฐC for long term storage and refrigerated at 2-8ยฐC for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | ADAM22 |
| Gene ID | 53616 |
| Uniprot ID | ADA22_HUMAN |
| Immunogen | A synthetic peptide from cytoplasmic domain of mouse ADAM22 (Metalloproteinase-disintegrin ADAM22-3) conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | Cytoplasmic Domain |
| Specificity | Specific for ADAM22. |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 22Adam 22Metalloproteinase-Disintegrin Adam22-3Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 |
| Database Links | Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionAxon |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 22 antibodyAnti-Adam 22 antibodyAnti-Metalloproteinase-Disintegrin Adam22-3 antibodyAnti-Metalloproteinase-Like - Disintegrin-Like - And Cysteine-Rich Protein 2 antibodyAnti-ADAM22 antibodyAnti-MDC2 antibody |
Information sourced from Uniprot.org