Anti-ADAM12 antibody (100-180) (STJA0006440)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human ADA12 AA range: 100-180
General Information
| Short Description | Rabbit polyclonal anti-Disintegrin and metalloproteinase domain-containing protein 12 (100-180) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ADAM12 |
| Gene ID | 8038 |
| Uniprot ID | ADA12_HUMAN |
| Immunogen | Synthesized peptide derived from human ADA12 AA range: 100-180 |
| Immunogen Region | 100-180 |
| Specificity | This antibody detects endogenous levels of human ADA12 |
Additional Info
| Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
| Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
| Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12Adam 12Meltrin-Alpha |
| Database Links | Reactome: R-HSA-177929Reactome: R-HSA-8941237 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: SecretedIsoform 3: SecretedIsoform 4: Secreted |
| Alternative Antibody Names | Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 12 antibodyAnti-Adam 12 antibodyAnti-Meltrin-Alpha antibodyAnti-ADAM12 antibodyAnti-MLTN antibodyAnti-UNQ346 antibodyAnti-PRO545 antibody |
Information sourced from Uniprot.org