• Immunofluorescence analysis of NIH/3T3 cells using ACVR2A Rabbit polyclonal antibody (STJ22506) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of paraffin-embedded mouse brain using ACVR2A antibody (STJ22506) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using ACVR2A antibody (STJ22506) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human lung using ACVR2A antibody (STJ22506) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Western blot analysis of extracts of A-431 cells, using ACVR2A antibody (STJ22506) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 180s.

Anti-ACVR2A antibody (20-513) (STJ22506)

SKU:
STJ22506

€211.88 - €561.88
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ACVR2A (20-513) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:100-1:500
IHC-P 1:100-1:200
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACVR2A
Gene ID: 92
Uniprot ID: AVR2A_HUMAN
Immunogen Region: 20-513
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-513 of human ACVR2A (NP_001607.1).
Immunogen Sequence: AILGRSETQECLFFNANWEK DRTNQTGVEPCYGDKDKRRH CFATWKNISGSIEIVKQGCW LDDINCYDRTDCVEKKDSPE VYFCCCEGNMCNEKFSYFPE MEVTQPTSNPVTPKPPYYNI L
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.
Protein Name Activin Receptor Type-2a
Activin Receptor Type Iia
Actr-Iia
Actriia
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Activin Receptor Type-2a antibody
Anti-Activin Receptor Type Iia antibody
Anti-Actr-Iia antibody
Anti-Actriia antibody
Anti-ACVR2A antibody
Anti-ACVR2 antibody

Information sourced from Uniprot.org

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