| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Actin-like protein 7A is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACTL7A |
| Gene ID: | 10881 |
| Uniprot ID: | ACL7A_HUMAN |
| Specificity: | This antibody detects endogenous levels of ACTL7A at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human ACTL7A |
| Function | Essential for normal spermatogenesis and male fertility. Required for normal sperm head morphology, acroplaxome formation, acrosome attachment, and acrosome granule stability. May anchor and stabilize acrosomal adherence to the acroplaxome at least in part by facilitating the presence of F-actin in the subacrosomal space. May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis. |
| Protein Name | Actin-Like Protein 7aActin-Like-7-Alpha |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonGolgi ApparatusNucleusCytoplasmic VesicleSecretory VesicleAcrosomeDetected At The Golgi Apparatus During Acrosome BiogenesisDetected At The Subacrosomal Layer In Round SpermatidsDetected In Sperm Head And Tail |
| Alternative Antibody Names | Anti-Actin-Like Protein 7a antibodyAnti-Actin-Like-7-Alpha antibodyAnti-ACTL7A antibody |
Information sourced from Uniprot.org
