Anti-Activin Receptor Type IIA antibody [R04-4G9] (STJA0037345)

SKU:
STJA0037345
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-Activin Receptor Type IIA for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R04-4G9
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
Formulation:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:ACVR2A
Gene ID:92
Uniprot ID:AVR2A_HUMAN
Immunogen:A synthesized peptide derived from human ACVR2A
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.
Protein Name Activin Receptor Type-2a
Activin Receptor Type Iia
Actr-Iia
Actriia
Database Links Reactome: R-HSA-1181150
Reactome: R-HSA-1433617
Reactome: R-HSA-1502540
Reactome: R-HSA-201451
Reactome: R-HSA-9839406
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Activin Receptor Type-2a antibody
Anti-Activin Receptor Type Iia antibody
Anti-Actr-Iia antibody
Anti-Actriia antibody
Anti-ACVR2A antibody
Anti-ACVR2 antibody

Information sourced from Uniprot.org