| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Activin Receptor Type IIA for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R04-4G9 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | ACVR2A |
| Gene ID: | 92 |
| Uniprot ID: | AVR2A_HUMAN |
| Immunogen: | A synthesized peptide derived from human ACVR2A |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6. |
| Protein Name | Activin Receptor Type-2aActivin Receptor Type IiaActr-IiaActriia |
| Database Links | Reactome: R-HSA-1181150Reactome: R-HSA-1433617Reactome: R-HSA-1502540Reactome: R-HSA-201451Reactome: R-HSA-9839406 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Activin Receptor Type-2a antibodyAnti-Activin Receptor Type Iia antibodyAnti-Actr-Iia antibodyAnti-Actriia antibodyAnti-ACVR2A antibodyAnti-ACVR2 antibody |
Information sourced from Uniprot.org